Determination of static and dynamic properties of muscle from microendoscopy sarcomere images

A recently developed SHG microendoscope allows for in vivo imaging of sarcomeres, the basic contractile unit of muscle, in humans for the first time. The static images and dynamic line scans over time provide important information about muscle function and health. The goal of this project was to extract length from static images and dynamic timing properties from dynamic images as automatically as possible. Fourier Transform techniques are used for static images, and edge detection and image tracking are used for dynamic images. Keywords—imaging; sarcomeres; muscle